Researchers are Closing In on a 'Universal' Flu Vaccine

The Weather Channel reports:
One main reason humans need to get a flu vaccine annually: flu strains mutate regularly so vaccines need to be slightly altered every year. During past flu seasons, the CDC has noted a vaccine effectiveness range between 40-60%, and a reduced the risk of flu-related illness by 40-60% within the overall population. There are, however, several 'universal' flu vaccines currently being studied that aim to make annual flu vaccinations a thing of the past. In fact, according to the American Society for Microbiology, some of these vaccine candidates are in phase 2 and phase 3 trials right now.

Now UPI reports:

Researchers believe they are one step closer to a 'universal' flu vaccine, even as concerns over the seasonal virus move to the back burner during the COVID-19 pandemic. T cells found in the lungs may hold the key to long-lasting immunity against influenza A, the more common and often more severe form of the virus, according to the researchers behind a study published Friday by Science Immunology.

These cells, which the researchers call resident helper T cells, help the body initiate antiviral responses against new influenza strains even after experience with only one type of the virus, the researchers said. This type of 'generalized' immune response, against all virus strains, is not possible with the currently available yearly vaccine formulations, they said.

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