MicroRNA Pioneers Win Nobel Prize in Medicine

American scientists Victor Ambros and Gary Ruvkun won the Nobel Prize in Physiology or Medicine on Monday for discovering microRNA, tiny molecules that regulate gene expression. Their groundbreaking work in the 1990s revealed a new layer of genetic control, opening fresh avenues for understanding human development and disease.

Ambros first identified microRNA in 1993, while Ruvkun later found similar molecules in humans and other species. These RNA fragments, about 100 times smaller than typical messenger RNA, can silence genes and fine-tune protein production. The discovery has spurred research into potential treatments for cancer, heart disease, and neurological disorders. Several biotechnology companies are now developing drugs that target or mimic microRNAs.

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