Pre-Lunch Coffee Drinkers Enjoy Lower Risk of Death, Analysis Finds

An anonymous reader quotes a report from The Guardian: People who get their coffee hit in the morning reap benefits that are not seen in those who have shots later in the day, according to the first major study into the health benefits of the drink at different times. Analysis of the coffee consumption of more than 40,000 adults found that morning coffee drinkers were 16% less likely to die of any cause and 31% less likely to die from cardiovascular disease during a 10-year follow-up period than those who went without. But the benefits to heart health appeared to vanish in people who drank coffee throughout the day, the researchers found, with medical records showing no significant reduction in mortality for all-day drinkers compared with those who avoided coffee.

The study suggests that a morning dose of coffee is better for the heart than an evening one, but it does not explain why. One possible explanation is that drinking coffee later in the day can disrupt circadian rhythms and levels of hormones such as melatonin. This in turn affects sleep, inflammation and blood pressure, all of which can harm heart health. In an accompanying editorial, Prof Thomas Luscher, a consultant cardiologist at the Royal Brompton and Harefield hospitals in London, notes that many all-day drinkers sleep poorly, adding that coffee seems to suppress melatonin, a hormone that is important for inducing sleep in the brain. The effects are driven largely by caffeine, but coffee contains hundreds of other bioactive compounds that affect our physiology. The researchers say some substances in the blood that drive inflammation often peak in the morning and could be countered by anti-inflammatory compounds in a morning coffee. 'This explanation applies to both caffeinated and decaffeinated coffee,' they write. 'Overall, we must accept the now substantial evidence that coffee drinking, particularly in the morning hours, is likely to be healthy,' Luscher writes. 'Thus, drink your coffee, but do so in the morning!'

The study has been published in the European Heart Journal.

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